Male infertility (oligozoospermia)
Oligozoospermia
Definition: sperm count < 20 millions / ml, but not completely absent (azoospermia). The sperm is a carrier / transporter cell for male genetic material. Carries it to the ovum, and fuses with it, to form a zygote (mini human form)
(World Health Organization, 1999)
Table 1. Normal values of semen variables, WHO standard
| Volume | 2.0 ml or more |
|---|---|
| pH | 7.2-7.8 |
| Sperm concentration | 20x106 spermatozoa / ml or more |
| Total sperm count | 40x106 spermatozoa ml or more |
| Motility | 50% or more with forward progression (i.e., categories (a) and (b); Section 2.4.2) or 25% or more with rapid linear progression (i.e. category (a)) within 60 min after collection |
| Morphology | 50% or more with normal morphology |
| Viability | 50% or more alive. i.e. excluding dye |
| White blood cell | Fewer than 1x106 / ml |
| Zinc (total) | 2.4 micromol or more per ejaculate |
| Citric acid (total) | 52 umol (10 mg) or more per ejaculate |
| Fructose (total) | 13 micromol or more per ejaculate |
| MAR test | Fewer than 10% spermatozoa with adherent particles |
| Immunbead test | Fewer than 10% spermatozoa with adherent beads |
Obligatory sperm counts for
Spontaneous pregnancy > 20 million / ml
Artificial insemination > 5 million / ml
IVF – few sperms extracted even from the testis
Sperm has some interesting unique facts
- The only meiotic cell in a human body
- Highly phenotypic transformation in structure
- Highly competitive cells – millions fighting for just 1 ovum
- One of the migrative / motile cells. No other cell has a tail!
- One of the fusion cells
- Very high proliferation rates (millions produced daily)
- High disposal rates (one copulation releases millions)
- The only transmigrating cell, produced in one body (male) and working in the other body (female)
- One of the banked cell (semen bank)
- Commercial cell – high marketability, high economic values (IVF centers)
- Cell of partnership (with ovum)
- A source of medical litigation
- Has few subcellular organelles
- Uses proton-motive force (H+ /pH) for motility (others use ATPs from mitochondria)
- A much donated cell (after blood)
- A cause for attention by police / judges / yogis
- The only cell stored both inside and outside body [semen bank]
- The highest target for legal / illegal pharmaceuticals
- Many were punished for depositing at wrong places. Even quarrels / wars occurred about their such deposition
Our focus was mainly on those cases, falling between 1.5 to 20 million / ml, as these cases are abundant and easily cured by HOM.
Important causes
- Varicocele / hot environment occupations
- Past history of mumps / TB / gonorrhea
- Addictions – Smoking / opioids (opium / heroin etc)
- Endocrinal
Spermatogenesis
It involves proliferation, meiosis and differentiation stages running through
cell of spermatogonia A ⇒ spermatogonium B (32 cells) ⇒ Primary spermatocyte (64 cells) ⇒ Secondary spermatocyte (128 cells) ⇒ Spermatids (256 cell) Reorganize to sperms
Mature spermatozoan developed are stored in epididymis, waiting for release and fertilizing ovum.
Role of homoeopathy in oligozoospermia
Our research found that Homoeopathic drugs are basically regenerative types. They mostly act through regeneration (replacing old / damaged tissues by new younger tissues) rather than repair (old tissues repair through fibrosis).
They can signal for stem cell enhancement, thereby enhancing the pool of stem cells / progenitor cells. They are governed through specific signaling transcription factors or growth factors like FGF / Oct 4 / Wnt / BMP / Nanog / Hedgehog / Sonic Hedgehog / Notch / Noggin / GDNF, etc.
Differential combination (cocktail) of above factors will promote / demote particular stem cells & their differentiation.
Surprisingly, the cocktails that were used during Embryogenesis, are reused to regenerate the specific tissue / organ. Regeneration is a sort of mini embryogenesis.
Homoeopathic drugs can enhance this cocktails and can regenerate tissues faster; it is not surprising that Homoeopathy has high number of proving symptoms in located in hair / skin, sex, blood and intestine (all 4 are fast regenerating tissue depending heavily on stem cells / PG cells).
Our statistics
We have treated > 15,000 cases of oligozoospermia with success rate about 85% in selected patients. The count improved within 1 to 2 months and the majority of them had with conception within 6 months and live births thereafter.
- Azoospermia
- Count < 1.5 million / ml
- Abnormal cells > 50 – 60%
- Progressive motility < 10%
- Low semen volume < 0.5 ml
Fortunately, such extreme cases are low in number, so on average Homeopathy has a high success rate.
Varicocele is not a deterrent (has high success rate with homeopathy)
Hom Drugs Can
- Raise count 2 to 6 times in 1 to 2 months
- Raise motility by 2 to 3 times
- Decrease abnormal cells
- Raise volume of semen
LIVE PREGNANCY RATE IS VERY HIGH WITH HOMOEOPATHY